Academic Health Center

University of Minnesota Genomics Center

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News & Announcements

UMGC is hosting a special seminar with Olink Bioscience

Please join us on Friday, March 20, from 12:00-1:00 PM in 1-125 CCRB (Cancer & Cardiovascular Research Building). 

Speaker: Andrea Ballagi, M.D., Ph.D., Chief Operating Officer, Olink Bioscience

Title: Proseek Multiplex: Simultaneous, Immunoassay-based, Genomics-powered Quantification of 92 Proteins from 1 ul Sample.

Proseek Multiplex is based on a combination of Proximity Extension Assay (PEA) and ultra-high-throughput real-time Q-PCR. In PEA, 92 pairs of antibodies -- each pair specific to a single target antigen -- are equipped with DNA reporter molecules. When binding to their target, the antibody pair bring the reporters into close proximity, where they extend and give rise to a DNA amplicon of unique sequence. This amplicon is subsequently quantified by real-time PCR on the Fluidigm BioMark HD platform. One "run" therefore represents the quantification of 92 proteins across 90 samples (8,280 data points).

Proseek Multiplex can provide accurate quantification below picogram/ml levels in small samples (1 ul) from needle biopsies or microdialysis. This minimal sample consumption makes Proseek Multiplex especially suitable for mining biobanked serum samples for new multivariate biomarker signatures.

During the seminar, we will describe the details of a pilot project grant -- jointly offered by Olink and the UMGC -- providing no-cost testing of Olink Bioscience's Multiplex kits. We will be accepting experimental proposals for testing of their Cardiovascular, Inflammation, and Oncology panels. Further details of the Olink Grant Program are available online.

This is a great opportunity to learn more about Olink Bioscience's technologies. individuals who are interested in the Olink Grant Program are strongly encouraged to attend. We have set aside time after the Seminar for discussion and extended Q&A with Dr. Ballagi.

 

UMGC is co-sponsoring the Lecture Series on Law, Health & the Life Sciences

Please view lecture dates and registration at http://consortium.umn.edu/lecturesconferences/lectures/lhls/home.html.

 

Thursday, February 12, 2015, from 11:30 AM to 1:00 PM in the Best Buy Theater of Northrop Auditorium

Heidi L. Rehm, PhD, FACMG "Genomic Variant Interpretation: The Good, the Bad, and the Uncertain"

 

Thursday, March 12, 2015, from 11:30 AM to 1:00 PM in the Mississippi Room of Coffman Memorial Union

Rex Chilsholm, PhD "Progress Toward Personalized Medicine and the Challenges of Integrating Genomics into Electronic Health Records"

 

Thursday, April 16, 2015, from 11:30 AM to 1:00 PM in the Best Buy Theater of Northrop Auditorium

Muin J. Khoury, MD, PhD "When Should We All Have Our Genome Sequenced? Assessing the Public Health Implications"

 

GenoFest 2014

On October 23, we will host our annual open house and technology symposium from 9:00 AM to 3:00 PM for registration click here. Presentations will be broadcast live at http://mediasite.uvs.umn.edu/Mediasite/Viewer/?peid=2d802188a84b4124bfc69525e4857cd1.

 

Dr. Beckman mentioned Illumina's documents in his presentation.

View Illumina's library creation poster at http://www.illumina.com/content/dam/illumina-marketing/documents/applications/ngs-library-prep/ForAllYouSeqMethods_v19.pdf

View Illumina's sequencing methods review at http://applications.illumina.com/content/dam/illumina-marketing/documents/products/research_reviews/sequencing-methods-review.pdf

 

 

GenoFest 2013

The presentations are archived and can be viewed at http://mediasite.uvs.umn.edu/Mediasite/Viewer/?peid=6d31243c5d0b45a3b5b057d714d9bf8a.

 

Dear UMGC Clients,

We are delighted to announce that thanks to financial support from a university-wide consortium of administrators, we have been able to lower our rates significantly.

Beginning with fiscal year 2013, funds have been provided by the following:

• Academic Health Center (AHC)
• Office of the Vice President for Research (OVPR)
• Medical School
• College of Biological Sciences (CBS)
• College of Veterinary Medicine
• College of Food, Agriculture and Natural Resource Sciences (CFANS)
• College of Pharmacy
• Dental School
• UMN Duluth
• College of Liberal Arts (CLA)
• School of Public Health
• College of Education and Human Development.

Although rates have not decreased for all services, most have benefited, and next-generation sequencing rates have been decreased by 40%-60%. Next-generation library creation rates have dropped by 20% or more.

Over the coming year, the UMGC plans to use newly acquired subsidies to improve our services in qualitative ways as well as offering a wider array of next-generation applications, improving turnaround time, and putting in place online tools for interacting with and tracking UMGC projects.

 

- University of Minnesota Genomics Center Staff

 

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  • Last modified on March 13, 2015